Clinical evaluation of the effect of acentric double pedicle graft with and without the use of platelet-rich fibrin (PRF) on root coverage outcomes in class I and II Miller root recessions: A randomized clinical trial

Background. Acentric double pedicle graft is an alternative to double pedicle graft, which can improve clinical outcomes by removing tension in sutures. This study examined the effect of using platelet-rich fibrin (PRF) on the success rate of acentric double pedicle graft in treating patients with Miller Class I and II recessions. Methods. A total of 16 Miller Class I and II lesions were studied in 8 patients. The samples were divided into two groups in terms of PRF use: with PRF and without PRF. Indices, including recession depth, width of keratinized gingiva and pocket depth, were measured with a standard Michigan O probe with Williams marking. Six months later, Kolmogorov-Smirnov test and Wilcoxon nonparametric test were applied with SPSS17 to analyze data. Results. The recession depth, width of keratinized gingiva, and increased root coverage exhibited a significant difference between the two groups after surgery, but no significant difference was found in pocket depths. Conclusion. Applying PRF with acentric double pedicle graft reduced the recession depth, increased the width of keratinized gingiva and enhanced the extent of root coverage when compared with the situation where PRF was not used. Therefore, this study supports the use of PRF with acentric double pedicle graft in root coverage treatments.