Akande, Tunji (2016) Early Detection of Prostate Cancer: Immunoassay for Serum Prostate Specific Antigen (PSA) Tumor Marker. International Journal of Biochemistry Research & Review, 12 (1). pp. 1-8. ISSN 2231086X
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Abstract
Background: Serum tumor markers are widely used clinically for monitoring response to therapy and detecting cancer recurrence. However, only a limited number of them have been effectively used for the early detection of cancer.
Objective: To review serum tumor markers used clinically, for the early detection of prostate cancer.
Methods: Literature review of serum tumor marker that have been widely accepted for the early detection of prostate cancer.
Results: In Nigeria only prostate specific antigen (PSA) has been clinically used for the early detection of prostate cancer. The analytical and clinical issues linked to its use were discussed.
Conclusion: Few serum tumor markers have been used effectively for the early detection of cancer, mainly due to their limited diagnostic sensitivity and specificity. PSA is the only tissue-specific marker identified, but it is not specific for prostate cancer. Various approaches have been developed to improve the clinical performance of PSA for the early detection of prostate cancer.
Item Type: | Article |
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Subjects: | Open Digi Academic > Biological Science |
Depositing User: | Unnamed user with email support@opendigiacademic.com |
Date Deposited: | 10 Jun 2023 07:05 |
Last Modified: | 06 Sep 2024 08:23 |
URI: | http://publications.journalstm.com/id/eprint/844 |